It depends, what codes are you specifically talking about? It is easier to help with more specifics. What are you trying to bill?
For example, if you are talking about a hammertoe (28285) that would be reported on separate lines with the T mods per toe. You also have to understand the MUE rationale reason.
My 1st question is always, "Was it coded correctly with the correct codes in the 1st place?"
Then start breaking it down if there are multiple lines.
Are the diagnosis pointers assigned correctly?
When you are talking foot and ankle (as with everything else) it is really important the codes are correct, the modifiers and the ICD-10s are exact. Like, if you had three toes but you assign all 3 ICD-10 to every line, that won't fly.
It's not just the MUEs and MAIs, you have to check the actual NCCI manual too.
https://www.cms.gov/files/document/medicare-ncci-policy-manual-2024-chapter-4.pdf
H. Medically Unlikely Edits (MUEs)
2. Providers/suppliers should be cautious about reporting services on multiple lines of a claim using modifiers to bypass MUEs. The MUE values are set so that such occurrences should be uncommon. If a provider/supplier does this frequently for any HCPCS/CPT code, the provider/supplier may be coding units of service (UOS) incorrectly. The provider/supplier may consider contacting their national healthcare organization or the national medical/surgical society whose members commonly perform the procedure to clarify the correct reporting of UOS.
See here: V. Medically Unlikely Edits (MUEs)
Spine codes make sense with one line and multiple units for the add-ons because it is additional levels. (e.g. 22614).