If the physician removes the polyps via different methodologies, (i.e. snare, hot biopsy forceps, or cold biopsy forceps) and the polyp is in a different region of the colon, then yes absolutely!! Please see below:
45380: colonoscopy, flexible, proximal to splenic flexure; with biopsy, single or multiple
1. The physician performs the colonoscopy and obtains tissue samples
2. This code can be reported ONCE regardless of the number of biopsies taken
3. According to CPT assistant, July 2004, this code is also to be used to describe polypectomy with cold biopsy forceps
4. If the physician does remove a polyp or other lesion with a different technique and then takes a biopsy of a separate lesion this code may be reported in addition with the appendage of -59 modifier.
Hope this helps!