You don't need a 25 modifier when you are doing diagnostic testing on the same DOS.You only use the 25 modifier when you are billing a separate E/M SERVICE, such as a foreign body removal. Most carriers will not reimburse for the 92250 and 92133/92134 being done on the same DOS because they are both considered imaging procedures which image the same part of the eye. Theoretically, according to the CCI edits, you can bill those two tests on the same DOS if you use a 59 modifier. However, I would STRONGLY encourage you NOT to do that since over use of the 59 modifier may make you an audit target.
Realize one other thing that many providers and billers don't pay attention to. It's called MPPR (Multiple Procedure Payment Reduction). If you do more than one diagnostic test on the same date of service, Medicare, and other carriers, will pay you full fee for the higher reimbursing procedure but will reduce the reduce the reimbursement for the second test by anywhere from 50% up to 100%. I know that most providers want to decrease the number of times a patient has to return to their offices. However, for chronic conditions, such as glaucoma and AMD, where you see a patient every few months, there is no reason to stack multiple tests on the same DOS. Do one test at one visit and then do the other test at the next visit.