The code 15271 and similar have a wound prep and debridement factored into the application, thus, billing 15002 at the same visit is not appropriate and it should only be billed once per wound. When it is determined that the patient would benefit from skin sub, the wound prep would be performed (15002/3 ankle/leg and 15004/5 foot) and the prep code is billed. The patient then returns for the application of the skin sub or allograft on a subsequent visit and the application code as well as the product code is billed. CMS has an LCD for skin substitutes, pull that for your MAC. It is very specific about documentation as well as how many grafts are appropriate. Within the LCD, under "Limitations" it states
1. Use of surgical preparation services in conjunction with routine, simple and/or repeat application of skin substitute grafts is not reasonable and necessary and will be denied accordingly.
2. Most repeat applications of skin replacement materials will not require separate debridement procedures. Such procedures may be subject to pre or post payment medical review. If documentation does not support cross contamination requiring extended cleansing and removal of appreciable amounts of devitalized tissue was performed, the service will be denied.
3. Clean and free of necrotic debris or exudate