CPT^® 0473U, Under Proprietary Laboratory Analyses

Summary

This is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0473U only for xT CDx from Tempus AI Inc. This test uses next–generation sequencing (NGS) to analyze the DNA of 648 genes from a solid tumor sample, which is preserved using formalin–fixed paraffin–embedded (FFPE) techniques. The tumor DNA is compared against DNA from a normal specimen (either blood or saliva) to detect genetic differences such as sequence variants, insertions and deletions, copy number variants, and rearrangements. Additionally, the test assesses microsatellite instability and calculates the tumor mutation burden, providing comprehensive insights into the tumor’s genetic landscape.

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