Not all AI is created equal, and knowing the nuances will affect your code categorization. As you have perused your 2023 CPT® code book, taking note of all the new, revised, and deleted codes and guidelines, you may not have focused on the appendices. But there is a new addition that you’ll want to review — Appendix S. The new appendix, “Artificial Intelligence Taxonomy for Medical Services and Procedures,” provides guidance for “classifying various artificial intelligence (AI) applications for medical services and procedures.” With AI being an ever-evolving focus in healthcare, you’ll want to read on to learn more about CPT® guidance for handling AI-related procedures. Get Up to Speed With the AI Appendix The CPT® Editorial Panel decided to add Appendix S to the CPT® code set during the September 2021 meeting. The appendix went into effect on Jan. 1, 2022, to provide guidance on coding for AI applications. Since the appendix wasn’t effective until the start of 2022, it wasn’t present in the published 2022 CPT® code book. However, the 2023 CPT® code book has the AI guidance in Appendix S. “AI needs a descriptive framework that is used to develop the coverage that, in turn, will adequately pay for expert systems, machine learning, and the algorithm-based services,” said Robert Jarrin, JD, managing member of The Omega Concern LLC in the “Coding, Coverage, and Payment for AI Medical Services” segment during the “An ONC Artificial Intelligence Showcase – Seizing the Opportunities and Managing the Risks of Use of AI in Health IT” virtual event on Jan. 14, 2022. Jarrin added that Medicare payment rates include direct and indirect practice expenses (PE); the latter’s values are based off the Physician Practice Information survey conducted in 2007 and 2008 — “way before we actually had tangible AI in healthcare.” The emerging technologies tend to rely on fees tied to software, licensing, and analysis, rather than the typical equipment and hardware purchases. “Coding will need to reflect AI, as in the work performed by machines, which is why the AMA created Appendix S ... as a taxonomy to provide guidance for classifying AI,” Jarrin said. “I think it’s a testimony to how important this is that the AMA chose to release this taxonomy a full year in advance of when it would normally release a new code. This taxonomy is intended to cover not only AI in the formal sense like machine learning, but also what we might call expert systems, and that is the advanced use of computer technology in order to augment the role of the physician,” said Richard Frank, MD, PhD, CMO Siemens Healthineers, member of CPT® Editorial Panel, who co-presented with Jarrin during the virtual event. Understand the 3 As of AI CPT® Coding Guidelines The CPT® AI taxonomy appendix categorizes AI into three main hierarchies based on “the clinical procedure or service provided to the patient and the work performed by the machine on behalf of the physician or other qualified healthcare professional (QHP).” These AI classifications are as follows: Assistive AI is the work done by the machine to only detect clinically relevant data. A physician or other QHP is required to interpret the data and report the results. Augmentative AI occurs when the machine performs the work and analyzes or quantifies the data “in a clinically meaningful way.” This category also requires a physician or QHP to interpret and report the data. With autonomous AI, the machine performs the work, then automatically analyzes the data, interprets the information, and produces clinically relevant conclusions independently without physician or QHP involvement. Learn the Levels of Autonomous AI Since autonomous AI can operate nearly free of human interaction, the CPT® Editorial Panel felt the need to establish different levels of autonomy. “We decided there needed to be at least three levels within [autonomous AI]; we considered more, but I think the simpler, the better. As long as this covers the range of what we expect autonomous devices to be doing,” Frank said. The three levels of autonomous AI differ on the amount of physician or QHP involvement as explained below: Could the AI Coding Framework Anticipate Future Uses? Appendix S guidelines indicate that there isn’t a certain product, service, or procedure where AI is necessary to describe the intended medical use. As a result, the appendix doesn’t list specific codes for which the guidelines could apply, although example codes are listed as references. According to the presenters, the CPT® Editorial Panel created the taxonomy to define the relationship between the work completed by the machine and the work done by a human, as well as show the relevance to AI. “This taxonomy, this framework for AI code descriptors, anticipates what features that will be, as well as what business models there may be,” Frank said.