Code 86051 describes a test to identify an antibody to aquaporin–4, typically in a serum specimen. The lab method for this test is enzyme–linked immunosorbent assay (ELISA). The presence of the aquaporin–4 antibody is a key marker for neuromyelitis optica (NMO), which is an autoimmune disease characterized by optic nerve and possibly brain stem and spinal cord involvement that is sometimes misdiagnosed as multiple sclerosis (MS).
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