CPT® 81464, Under Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

The Current Procedural Terminology (CPT®) code 81464 as maintained by American Medical Association, is a medical procedural code under the range - Genomic Sequencing Procedures and Other Molecular Multianalyte Assays.

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Summary

The lab analyst performs a liquid biopsy using a plasma specimen to identify cell–free DNA (cfDNA) or DNA/RNA for a genomic sequence analysis panel. The test evaluates nucleic acid sequence variants, copy number variants, and rearrangements relevant to solid organ neoplasms. The test also evaluates other factors that may guide treatment options, such as microsatellite instability (MSI), which is an indicator of how likely the cells are to mutate, and tumor mutation burden (TMB), which is an indicator of the level of genetic mutations present in cancer cells.

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