CPT® 0456U, Under Proprietary Laboratory Analyses

The Current Procedural Terminology (CPT®) code 0456U as maintained by American Medical Association, is a medical procedural code under the range - Proprietary Laboratory Analyses.

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Summary

This is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0456U only for PrismRA® from Scipher Medicine®, performed on a whole blood specimen. The test includes next–generation sequencing (NGS) to evaluate gene expression of 19 genes and analysis of anticyclic citrullinated peptides (CCP) levels. The test uses algorithmic analysis of the findings and the patient’s sex, global assessment, and body mass index (BMI) to report a score that predicts nonresponse to tumor necrosis factor inhibitor (TNFi) therapy for rheumatoid arthritis.

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