Question: What are our best CPT® options when we’re coding for a prostate biopsy in the office? Florida Subscriber Answer: Many urology practices have three code options they rely on for in-office prostate biopsies, depending on the exact situation: Take note: As of Jan. 1, 2017, CPT® and CMS have indicated that when you’re billing for a transrectal biopsy of the prostate gland, should report either 76872 or 76942 – but not both. Select the code according to which sonogram is documented in the operative report.