Question: Illinois Subscriber Answer: Starting Jan. 1, you will be able to use one of two new fibrinolytic agent instillation codes depending on the treatment day: • For instillation on the initial day, use 32561 (Instillation[ s], via chest tube/catheter, agent for fibrinolysis [e.g., fibrinolytic agent for breakup of multiloculated effusion]; initial day). • If the pulmonologist instills the fibrinolytic agent on a subsequent day, assign 32562 (... subsequent day). Rule: You are correct to code for instillation of an agent for pleurodesis with 32560 both now and in 2010. The code currently reads "Chemical pleurodesis [e.g., for recurrent or persistent pneumothorax]." The code will specify agent instillation through a chest tube or catheter and give an example agent, talc, in 2010: "Instillation, via chest tube/catheter, agent for pleurodesis (e.g., talc for recurrent or persistent pneumothorax)." CPT 2010 further revises this code to remind you when it is appropriate to also code the chest tube insertion with 32551 (Tube thoracostomy, includes water seal [e.g., for abscess, hemothorax, empyema], when performed [separate procedure]).