Question: I need help locating the ICD-10 codes for use of high-risk medication during pregnancy. What should I report? Massachusetts Subscriber Answer: Since the drug monitoring is impacting the pregnancy, you would use a supervision of high-risk code for your primary diagnosis and a Z code to indicate which drug (if listed) as your secondary code. Look to O09.89- (Supervision of other high risk pregnancies) as your primary. You will need a 6th character to indicate the pregnancy’s trimester or whether the trimester is unspecified. Code O35.5- (Maternal care for (suspected) damage to fetus by drugs) is also an option, but most payers think this means drug addiction. For the Z code, if no other entry specifically states the medication you are looking for, try the “generic” code of Z79.899 (Other long term (current) drug therapy).