Primary Care Coding Alert

Primary Care Coding:

Take This Advice, Keep Your 2024-25 Winter Vaccine Coding Healthy

Keep your respiratory virus vaccine administration reporting on point.

Each year, respiratory viruses are responsible for huge numbers of illnesses, hospitalizations, and even deaths in the United States according to the Centers for Disease Control and Prevention (CDC). There are many types of respiratory viruses, including COVID-19, flu, and respiratory syncytial virus (RSV). The good news is there are actions your primary care practitioner (PCP) can take to help protect your patients and their families from health risks caused by these viruses.

Immunizations are a core prevention strategy to lower risk from respiratory viruses. For most people, that means getting a current flu and COVID-19 vaccine. For coders, however, that means keeping track of all the different vaccines that are available, and assigning the appropriate CPT® codes for both the vaccines and their administration. So, we’ve gathered together all of that information into this handy guide to keep your respiratory virus reporting current for this winter season.

Know How to Code for This Year’s Flu Products

All 2024-2025 seasonal influenza vaccines are trivalent. The following table lists them along with their related CPT® codes.

2024/2025 INFLUENZA VACCINE CODES

Manufacturer

Product Label Tradename

How Supplied

Age

CPT® Code

GlaxoSmithKline

FLUVARIX

SYRINGE, 0.5mL

6 months & older

90656

FLULAVAL

SYRINGE, 0.5 mL

6 months & older

90656

MedImmune, Inc.

FluMist trivalent

APPLICATOR, 0.2 mL

2 through 49 years

90660

Sanofi Pasteur Inc.

FLUBLOK (RIV3)

SYRINGE, 0.5 mL

18 years & older

90673

FLUZONE HIGH DOSE

SYRINGE, 0.5 mL

65 years & older

90662

FLUZONE (IIV3)

VIAL, 5 mL, MULTI-DOSE

6 months & older

90658

6 through 35 months

90657

SYRINGE/VIAL, 0.5 mL

6 months & older

90656

Seqirus Inc.

Flucelvax

SYRINGE, 0.5 mL

6 months & older

90661

VIAL, 5 mL, MULTI-DOSE

6 months & older

90661

Afluria

VIAL, 5 mL, MULTI-DOSE

3 years & older

90658

6 through 35 months

90657

SYRINGE, 0.5 mL SINGLE

3 years and older

90656

FLUAD

SYRINGE, 0.5mL

65 years & older

90653

 

Remember: In addition to the vaccine product, you should always use an administration code. The code you should use for the administration will depend on whether the vaccine is given alone or with other vaccines, the route taken for the administration, and whether counseling occurred. It may also depend on the payer in question.

When coding for influenza vaccination without physician counseling, you’ll use one of the following codes:

  • 90471 (Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections); 1 vaccine (single or combination vaccine/toxoid))
  • +90472 (…each additional vaccine (single or combination vaccine/toxoid) (List separately in addition to code for primary procedure))
  • 90473 (Immunization administration by intranasal or oral route; 1 vaccine (single or combination vaccine/toxoid))
  • +90474 (…each additional vaccine (single or combination vaccine/toxoid) (List separately in addition to code for primary procedure))

If your PCP provides immunization counseling, you should use 90460 (Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; first or only component of each vaccine or toxoid administered)) or +90461(…each additional vaccine or toxoid component administered (List separately in addition to code for primary procedure)).

Note that Medicare has its own, unique influenza immunization administration code. For Medicare patients, you should report G0008 (Administration of influenza virus vaccine).

Use the Correct COVID Codes

You should use the following CPT® codes to report the different COVID-19 vaccines:

2024/2025 COVID-19 VACCINE CODES

Manufacturer

Product Label

Tradename

How Supplied

Age

CPT® Code

Pfizer

COMIRNATY

30 mcg/0.3 mL

Ages 12 years and older

91320

Pfizer-BioNTech COVID-19 Vaccine

10 mcg/0.3 mL

Ages 5 through 11

91319

Pfizer-BioNTech COVID-19 Vaccine

3 mcg/0.3 mL

Ages 6 months through 4 years

91318

Moderna

SPIKEVAX

50 mcg/0.5 mL

Ages 12 years and older

91322

Moderna COVID-19 Vaccine

25 mcg/0.25 mL

Ages 6 months through 11 years

91321

Novavax

Novavax COVID-19 Vaccine, Adjuvanted

 5 mcg/0.5 mL

Ages 12 years and older

91304

You’ll use a different CPT® code, 90480 (Immunization administration by IM injection of SARS-CoV-2(coronavirus disease [COVID-19]) vaccine, single dose), to bill for the administration of the COVID-19 vaccine. You can use this CPT® code regardless of whether the provider has counseled the patient or caregiver about the vaccine.

Note that if your PCP administers the influenza or COVID-19 vaccine in a Medicare patient’s home, you may also report M0201 (Administration of pneumococcal, influenza, hepatitis B, and/or COVID-19 vaccine inside a patient's home; reported only once per individual home per date of service when such vaccine administration(s) are performed at the patient's home) in addition to the base vaccine administration code. However, you should only bill for the additional in-home payment amount if the sole purpose of the visit is to administer a COVID-19 vaccine. Don’t bill for the additional amount if your PCP provides and bills Medicare for another service in the same home on the same date.

And Get Ready for RSV in Adults …

RSV is a common respiratory virus that usually causes mild, cold-like symptoms. It can cause illness in people of all ages but may be especially serious for infants and older adults.

For adults age 75 and older and adults 60-74 at increased risk of severe RSV, the CDC recommends a single dose of any FDA-approved RSV vaccine. There are several RSV vaccines currently available for adults ages 60 and older:

FALL 2024/2025 RSV VACCINE CODES

Manufacturer

Product Label Tradename

How Supplied

Age

CPT® Code

GlaxoSmithKline

Arexvy

VIAL, 0.5 mL, reconstituted

60 years & older

90679

Pfizer Laboratories

Abrysvo

VIAL, 0.5 mL, reconstituted

60 years & older

90678

Pfizer Laboratories

Abrysvo

VIAL, 0.5 mL, SINGLE-DOSE

60 years & older

90678

Moderna US, INC.

mRESVIA

SYRINGE, 0.5 mL

60 years & older

90683

When billing for any of the RSV vaccine administrations for adults, you’ll reach for 90471 or +90472 as appropriate.

… and in Kids

There are two options for protection of infants against RSV. The CDC recommends a single dose of RSV vaccine from week 32 through week 36 of pregnancy and preventive antibodies given to infants under 6 months of age. You’ll use the following CPT® codes to report the vaccine product if delivered during pregnancy.

 

Manufacturer

Product Label Tradename

How Supplied

AGE

CPT® Code

Pfizer Laboratories

Abrysvo

VIAL, 0.5 mL, reconstituted

32-36 weeks gestational age

90678

VIAL, 0.5 mL, SINGLE-DOSE

90678

                                                                                                

Lastly, in 2023, the Food and Drug Administration (FDA) approved Beyfortus (nirsevimab), the first monoclonal antibody of its kind used to help protect infants and young children against RSV. Your PCP can administer Beyfortus to newborns and infants under 8 months born to mothers who did not get a maternal RSV vaccine. It should be given to babies shortly before the RSV season, or within one week after birth if born during October to March. Some babies with chronic conditions could need Beyfortus in the second year of life.

You should use the following CPT® codes to report the Beyfortus monoclonal antibody product:

Manufacturer

Product Label Tradename

How Supplied

 

CPT® Code

Sanofi Pasteur Inc.

BEYFORTUS

SYRINGE, 0.5 mL

Infants < 8 months, < 5 kg

90380

SYRINGE, 1 mL

Infants < 8 months, 5 kg+

90381

8-19 months, increased risk

 

In 2024, CPT® released 2 new codes specifically for reporting the administration and counseling of Beyfortus. The billing of the administration depends on whether the provider counseled the family about the injection. The distinction ensures accurate billing based on the level of service provided during the visit.

You should bill Beyfortus monoclonal antibody administration as follows:

  • Use 96380 (Administration of respiratory syncytial virus, monoclonal antibody, seasonal dose by intramuscular injection, with counseling by physician or other qualified health care professional) if the provider counseled the family about the injection during the visit.
  • Use 96381 (Administration of respiratory syncytial virus, monoclonal antibody, seasonal dose by intramuscular injection) if no counseling was provided.

The Bottom Line

Vaccines for influenza, COVID-19, and RSV are crucial for public health, especially during the winter months when these illnesses are more prevalent. Together, these vaccines play a vital role in preventing widespread illness, reducing healthcare burdens, and protecting vulnerable populations during the winter season.

Donna Walaszek, CCS-P, Northampton Area Pediatrics, Northampton Massachusetts