Tip: Count the number of body systems involved to make the right choice. Summertime is here, which means many of your patients will be spending more time outdoors. If a patient presents to your office with complications following a bee sting, how do you know whether to report an allergic reaction or something more serious, such as anaphylaxis? Consider the following case, then check out our expert's advice on how to handle similar situations. Scenario: Identify the Reaction Reason Your first thought might be to assign an allergic reaction diagnosis for the patient -- but that's not your best choice in this case. Although allergic reactions are a type of anaphylaxis, grouping them together when it's time to code will not only result in the wrong ICD-9 code, but will also undermine the severity of the encounter from the payer's perspective. Difference: "By definition, anaphylaxis syndrome is an explosive multisystem immune reaction," Linzer says. Generally, skin and respiratory symptoms appear first, but cardiac and gastrointestinal problems may also develop. Explanation: Additional: Finally, add E905.3 (Venomous animals and plants as the cause of poisoning and toxic reactions; hornets, wasps and bees) to identify the source of anaphylactic sydrome. Some payers might not accept external cause codes, but including E905.3 gives a more complete picture of the situation. Include E/M Code as Documentation Allows Assuming the FP injected the patient with an antigen mix to treat the condition, you'll need to code for that service. Report 95130 (Professional services for allergenimmunotherapy in prescribing physicians office or institution, including provision of allergenic extract; single stinging insect venom) for the injection. You might also be able to report an E/M code for the encounter. Diagnoses 989.5, 995.0, and E905.3 help support medical necessity for the antigen injection. Complete documentation of the patient's condition should allow you to submit the appropriate E/M code from the 99201-99215 series. Remember: Your final claim should include: