Question: Iowa Subscriber Answer: Your coding will involve one of the following ICD-9 codes: 394.x (Diseases of mitral valve), 395.x (Diseases of aortic valve), or 396.x (Diseases of mitral and aortic valves). After all, that was the primary reason the patient required the heart valve replacement (V42.2, Organ or tissue replaced by transplant; heart valve). Because your question does not specify any other details about the procedure, you will likely use one of two other codes to describe the disease that prompted the replacement of the valve. For patients with rheumatic involvement that does not include the aortic valve, you should use 394.x. For patients without rheumatic involvement, use 424.0 (mitral valve disorders).