Question: Can you tell me when to correctly append modifier 25 versus modifier 57? Nebraska Subscriber Answer: Append modifier 57 (Decision for surgery) only when the surgery is major, which means it has a 90-day global surgery period. "If the patient is having major surgery, which is a surgery that has a 90-day global surgical period, and the physician performs an E/M on the day before or day of the surgery, then use the 57 modifier," says Catherine Brink, BS, CMM, CPC, president of Healthcare Resource Management in Spring Lake, New Jersey. Tip: Suzan Hauptman, CPC, CEMC, CEDC, AAPC Fellow, senior principal of Ace Med Group in Pittsburgh, Pennsylvania, gives a helpful way to remembering this code by knowing it is a larger number than the modifier 25, thus it is used for major procedures as opposed to minor ones. "A/B MACs (B) may not pay for an evaluation and management service billed with the CPT® modifier 57 if it was provided on the day of or the day before a procedure with a 0 or 10-day global surgical period," according to the Medicare Claims Processing Manual 30.6.6. On the other hand, you should only append modifier 25 (Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service) to indicate a distinct E/M with a minor procedure (zero or 10-day global period) performed on the same day. Remember the following rules you must also adhere when appending modifier 25: