Question: Answer: Append modifier 25 (Significant, separately identifiable evaluation and management service by the same physician on the same day of the procedure or other service) to the E/M code to denote that it was significant and separately identifiable from the injection service. Next, report the injection code (such as 96372, Therapeutic, prophylactic, or diagnostic injection [specify substance or drug]; subcutaneous or intramuscular). Finally, report J3360 (Injection, diazepam, up to 5 mg) for the medication. Your best diagnosis choice is either a non-specific anxiety code, such as 300.00 (Anxiety state, unspecified) or 300.09 (Anxiety state; other), or the general symptom code for nervousness, 799.21 (Signs and symptoms involving emotional state; nervousness). Document: The nurse should complete an evaluation and management note to support billing 99211. This should include a history and assessment, including vital signs. Plus in conjunction with the physician, you should document the decision to proceed with the requested injection. The physician should countersign this note.