Answer: You should not be using place of service (POS) code 81, Independent Laboratory, for tests you perform in your independent lab. Code 69, Clinical laboratory (billing independently), is not a POS code, but is a Medicare provider specialty code, so you shouldn’t use that, either. Do this: You should submit claims using the POS code for the patient’s location when the specimen is taken. That means you’ll likely use one of the following POS codes instead of 81, especially for COVID-19 tests: Resources: For a list of POS codes and instructions for reporting them, see the Medicare Claims Processing Manual, Chapter 26, available at https://www.cms.gov/regulations-and-guidance/guidance/manuals/downloads/clm104c26pdf.pdf.