Question: What is the difference between the C-reactive protein and high-sensitivity C-reactive protein codes? Answer: C-reactive protein (CRP) is a blood test that measures a protein produced by the liver as a response to inflammation somewhere in the body.
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Physicians might order standard C-reactive protein tests to monitor a number of inflammatory conditions, such as rheumatoid arthritis. These tests do not accurately measure low levels of CRP. Use 86140 (C-reactive protein) to report the conventional CRP assay.
The high-sensitivity C-reactive protein (hsCRP) is a newer lab method that detects low levels of CRP using monoclonal antibodies and a turbidity measure. Quantifying lower levels of CRP can be important for evaluating increased risk of cardiovascular disease. Report hsCRP using 86141 (C-reactive protein; high sensitivity [hsCRP]).