Don't miss 7th digit 'A', 'D', or 'S.' ICD-9 2012 changes the term "anaphylactic shock" to "anaphylactic reaction," but ICD-10 will change it back when you begin to use the new codes on Oct. 1, 2013. If your lab bills for transfusion medicine services, and the physician notes that the patient has an anaphylactic reaction due to the transfusion, you should report the diagnosis as 999.41 (Anaphylactic reaction due to administration of blood and blood products) or 999.49 (Anaphylactic reaction due to other serum) starting Oct. 1. That's instead of 999.4 (Anaphylactic shock due to serum), which becomes inactive for ICD-9 2012. But 999.41 will crosswalk to T80.5xx- (Anaphylactic shock due to serum) when ICD-10 goes into effect. Problem: No problem: Capture Subsequent Encounters With 7th Digit ICD-10 requires a seventh digit for T80.5xx-. You must report the code with one of the following letters in the seventh position: Use the extension "A" when the patient is receiving active treatment for the transfusion-related anaphylaxis. "D" describes a subsequent encounter following the active treatment for routine care during recovery. Reserve "S" for an encounter for late effects -- a complication or condition that arises as a direct result of the initial transfusion-related anaphylaxis. Clarify 'x' and '-': Because "x" serves a specific purpose in ICD-10 codes, you can use a "-" instead of an "x" to indicate that you're not specifying a digit -- such as T80.5xx-.