Keep using 83890-83914 for most payers. Don't expect 101 new CPT® molecular diagnostics codes to solve your specificity and payment problems -- CMS has announced that they won't price the codes for 2012. "As Medicare goes, so go most payers," says William Dettwyler, MT-AMT, president of Codus Medicus, a laboratory coding consulting firm in Salem, Ore. Most insurers evidently plan to continue accepting the "stacking codes" (83890-83914, Molecular diagnostics; ...) in the coming year for tests they cover. "It would be best to contact your major payers before billing these tests in 2012," he says. Read on to learn when and how you might start to use the new CPT® molecular pathology codes. Watch for CMS Staged Implementation CMS notes in the 2012 Medicare Physician Fee Schedule (PFS) that the AMA Relative Value Scale Update Committee (RUC) reviewed over 100 new CPT® 2012 codes describing molecular pathology services, but "they will not be valid for Medicare purposes for CY [calendar year] 2012." The new molecular pathology codes appear in Addendum B to Medicare's PFS final rule with the procedure status indicator of I (Not valid for Medicare purposes. Medicare uses another code for the reporting and payment for these services). Hint of things to come: In tandem, the CPT® Editorial Committee will continue to monitor which code section(s) require revisions. The committee intends to offer special focus to molecular pathology, among other services, in 2013, said Peter A. Hollmann, MD, chair of the CPT® Editorial Panel, during the CPT® 2012 Annual Symposium. Use 'Stacking Codes' Now CMS says that for CY 2012, "Medicare will continue to use the current 'stacking' codes for the reporting and payment for [molecular pathology] services." That means for Medicare and most other payers, you'll ignore the new codes and report these tests just as you have in past years. In other words, report molecular assays using appropriate codes from the range 83890-83914. Each code describes a separate technique, such as nucleic acid extraction, gene amplification, or nucleic acid probes. Add them up: Pitfall: Prepare for 'Tiers' Even though most payers won't accept them in 2012, you need to start getting familiar with the new molecular pathology codes. CPT® 2012 introduces 92 specific codes for commonly-used genetic markers. The remaining new molecular pathology codes describe resource-based tests not listed in the first group. These are the "Tier 1" and "Tier 2" codes, respectively. Tier 1: Tier 2: Tier 2 includes a list of specific tests under each code. For instance, level 1 (81400, Molecular pathology procedure, level 1 [e.g., identification of single germline variant (e.g., SNP) by techniques such as restriction enzyme digestion or melt curve analysis]) includes tests such as ACE (angiotensin converting enzyme) (e.g., hereditary blood pressure regulation), insertion/deletion variant. Look ahead: