Question: How do I code a biopsy and removal of a colon polyp using a cold forceps technique? I see code options for hot biopsy forceps and snare techniques, but nothing referencing cold forceps. Illinois Subscriber Answer: Typically, the physician will only use a cold forceps technique to remove a portion of the tissue to have sent for biopsy. You may want to reevaluate the operative report to confirm that the provider is removing the entire polyp, rather than a portion for biopsy. The general consensus among most coders is that when the provider uses a technique other than snare or hot biopsy forceps, such as cold forceps, you should report code 45380 (Colonoscopy, flexible; with biopsy, single or multiple). However, a January 2004 CPT® Assistant article seems to state otherwise: While some coders use this CPT® Assistant article to argue in favor of the use of code 45380 to report polypectomies using a cold forceps technique, the answer seems to be ambiguous, at best. While the American Medical Association (AMA) states that 45380 does not describe a specific technique, it further goes on to explain that 45380 typically involves the removal and biopsy of a “small” piece of tissue. Still, 45380 appears to be the “best” option available, despite its shortcomings. However, you also may consider the option of applying code 45399 (Unlisted procedure, colon). It is advised that you contact the payer to confirm that the operative report warrants submission of either code 45380 or 45399.