Timeframes, types of medications dictate your coding. Physicians administer hyaluronate or hyaluronic acid injections (commonly known by brand names Synvisc, Synvisc-One, Hyalgan, Supartz, and others) for osteoarthritis of the knee, but you need to look beyond a simple code when reporting the procedures. Code confusion: Now that all hyaluronate injections fall under the same code, here are three checkpoints to keep in mind and help you calculate correctly. Verify the Type of Medication Physicians use hyaluronate injections to help alleviate the patient's pain due to osteoarthritis of the knee. The medications achieve the same purpose, and you report both types of injections with J7325 (Hyaluronan or derivative, Synvisc or Synvisc-One, for intra-articular injection, 1 mg). Correct coding depends on the medication used and the number of units you report. Synvisc-One is a one-shot injection equaling 6 cc of the medication. The patient sees your physician once for the full injection, which you report as 48 units of J7325 (2 cc = 16 g, so 6 cc = 48 mg). Physicians administer the other forms of hyaluronate as a series of injections instead of one shot at a single patient visit. Watch the dosage amounts closely so you'll report the correct number of J7325 units for each administration. Chart note: Injection: "Medicare will only reimburse for hyaluronate injections to treat osteoarthritis of the knee," says Mary Baierl, RHIT, CPC, CCA, CMT, a coder with BayCare Health Systems in Green Bay, Wis. You have several diagnosis options, so b e sure one of these applies to help smooth your claims processing: Anatomy note: Determine Whether E/M and Modifiers Apply Some visits for hyaluronate injections qualify for an E/M code or modifiers, but others don't. If the patient comes to your office specifically for a scheduled Synvisc-One injection, you'll only report the injection code. If, however, the physician completes another service during the visit, an E/M code might apply. Example: The orthopedist completes and documents a thorough examination. He advises the patient to go through a series of hyaluronate injections and the patient agrees. You can report an E/M code from 99212-99215 (Office or other outpatient visit for the evaluation and management of an established patient ...) in addition to 20610 and J7325. Append modifier 25 (Significant, separately identifiable evaluation and management service by the same physician on the same day of the procedure or other service) to the E/M code. You won't submit an E/M code for follow-up visits for the additional hyaluronate injections unless the physician completes an additional service during the visit. Global watch: Many patients receive hyaluronate injections to only one knee, but your physician might treat both knees at times. In that case, explain the situation by appending modifier 50 (Bilateral procedure) to 20610. List J7325 on the claim twice, with modifiers LT (Left side) and RT (Right side) appended.