Question: Wisconsin Subscriber Answer: High-grade PIN (PIN III) is a likely precursor of invasive prostate cancer. Because this is not the same as a benign hyperplasia, you should not classify the condition to the 600 category (Hyperplasia of prostate). Instead, you should code PIN III as carcinoma in situ (233.4). Although the neoplasm table in the ICD-9 manual's index does not offer enough information to help you choose 233.4 for PIN III, you will find a "PIN III" entry in the index itself. That entry points you to 233.4. On the other hand, you should report PIN I and PIN II using 602.3 (Dysplasia of prostate). This diagnosis represents a lesser degree of cellular abnormality of the prostate than PIN III. You also should not assign 185 (Malignant neoplasm of the prostate) for a PIN III diagnosis.