In some cases, the patient may receive an IV infusion and prolonged infusion initiation on the same day. If so, you may report 96413 (Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug) in addition to 96416 (Chemotherapy administration, intravenous infusion technique; initiation of prolonged chemotherapy infusion [more than 8 hours], requiring use of a portable or implantable pump) for Medicare payers. -Do not confuse -initial- with -initiation,-- warns Joyce Matola, billing manager for The Center for Cancer and Hematologic Disease in Cherry Hill, N.J.. -You may report only one -initial administration- per date of service. Initiation of a pump is not an initial service, and many times is subsequent to another chemotherapy service.- Example: During the FOLFOX 4 regimen, the patient may receive Oxaliplatin on day 1 at 85 mg/m2 as a two hour infusion, concurrently with FA 200 mg/m2/day, followed by bolus 5-FU 400 mg/m2 and a 22 hour infusion of 5-FU 600 mg/m2 for two consecutive days. Here, you would report: - the Oxaliplatin (J9263, Injection, oxaliplation, 0.5 mg) with 96413 and +96415 (Chemotherapy administration, intravenous infusion technique; each additional hour [list separately in addition to code for primary procedure]) - the 5FU (J9190) as +96411 ( Chemotherapy administration, subcutaneous or intramuscular; intravenous technique, each additional substance/drug [list separately in addition to code for primary procedure]) - the concurrent leucovorin with +90768 (Intravenous infusion, for therapy, prophylaxis or diagnosis [specify substance or drug]; concurrent infusion [list separately in addition to code for primary procedure]) - pump initiation with 96416.