Plus: Get a glimpse at ICD-10's R65.1x section. Don't Settle for a Single Code You should sequence the diagnosis for the underlying cause first, followed by the SIRS diagnosis. And remember to assign a fifth digit for 995.9x to describe the presence or absence of acute organ dysfunction, as explained below. Base Choice on 'Organ Dysfunction' For SIRS with organ dysfunction, you will need three ICD-9 codes: 1. First code the underlying condition (neoplasm). 2. Then report 995.94 (Systemic inflammatory response syndrome due to noninfectious process with acute organ dysfunction) for the SIRS. 3. Finally, use an additional diagnosis to specify the acute organ dysfunction (such as 584.5, Acute renal failure; with lesion of tubular necrosis). Watch for: Example: • 157.x (Malignant neoplasm of pancreas ...) as the primary diagnosis • 995.93 (Systemic inflammatory response syndrome due to noninfectious process without acute organ dysfunction) for SIRS without organ dysfunction. Be sure to pay attention to the note with 995.93 which specifies that you should code the underlying condition first, Avery advises. Unspecified: Caution: Separate SIRS From Sepsis Be sure your clinicians' documentation habits distinguish SIRS from sepsis because the oncologist's documentation must include the term "SIRS" for you to assign the 995.9x codes discussed above. Thorough documentation helps eliminate a guessing game when choosing the proper code, says Rita Huelar, CPC, a billing specialist with Nemours Health System in Jacksonville, Fla. "Sepsis and SIRS are not synonymous terms," Avery stresses. "Educate your physicians on how to properly document each by using the official ICD-9 guidelines to illustrate how complex the coding for these conditions can be and the importance of their documentation." ICD-9 definitions: Look Ahead to R65.1x in ICD-10 When you start using ICD-10 codes in 2013 in place of your trusty ICD-9 codes, your SIRS code options will look a little different: R65.10 -- Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction R65.11 -- Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction. Tip: Remember that the transition date for ICD-10 codes is Oct. 1, 2013, as CMS's Stewart Streimer noted during a CMS-sponsored open door forum. But today isn't too soon to start thinking about ICD-10, says Avery. The more familiar you are with the changes, the easier the transition will be. "Obtain education and understanding early on so that you will be well equipped. Start by speaking with your physicians now about improving their clinical documentation detail which will be the most important aspect for them and should be started prior to the change," Avery says. Coders also should be involved when practices communicate with "information system vendors (for EMR, claims processing, etc.) about their plans for the new code set implementation," advises Avery. ICD-10 resource: