Question: How do you code a history of elevated prostate-specific antigen (PSA)? AAPC Forum Participant Answer: There is no specific history code for elevated PSA levels, which often occur in patients with prostate cancer and various other noncancerous conditions. The best possible code match in this situation is probably Z87.448 (Personal history of other diseases of urinary system). Code choice in this case assumes that the elevated PSA history is not associated with a personal history of prostate cancer. If it is, then the correct personal history code to use would be Z85.46 (Personal history of malignant neoplasm of prostate).