Question: The treatment plan says the patient will receive chemotherapy by spinal "infusion." Which chemotherapy administration code should I use? Vermont Subscriber Answer: Terminology can be confusing if a provider doesn't use explanations that match CPT descriptors. The correct code for chemotherapy by "spinal infusion" is 96450 (Chemotherapy administration, into CNS [e.g., intrathecal], requiring and including spinal puncture).