Whether liver neoplasm is primary or secondary will change your coding. Good news: Start here: 96420 -- Chemotherapy administration, intra-arterial; push technique 96422 -- ... infusion technique, up to 1 hour +96423 -- ... infusion technique, each additional hour,(List separately in addition to code for primary procedure) 96425 --" ... infusion technique, initiation of prolonged infusion (more than 8 hours), requiring use of a portable or implantable pump. Compare 96420-96425 Applications Push: For an IA chemotherapy push, you should report 96420,says Davis. You should apply the same CPT definitions for a "push" to both IA and intravenous (IV) administration: (a) "an injection in which the healthcare professional who administers the substance/drug is continuously present to administer the injection and observe the patient" OR (b) "an infusion of 15 minutes or less." Infusion: Pump: Focus on Liver For Likely Diagnoses Two of the more common diagnoses treated by IA chemotherapy are primary liver neoplasm and a secondary liver neoplasm that metastasized from the colon. "The route of treatment [IA or IV] will not affect the diagnosis codes you use," says Tracy Helget, CPC, in the business office of Medical Associates of Manhattan, PA, in Kansas. The appropriate code for primary liver cancer, such as hepatocellular carcinoma, cholangiocarcinoma, or hepatoblastoma, is 155.0 (Malignant neoplasm of liver and intrahepatic bile ducts; liver, primary). When the colon neoplasm is primary and the liver neoplasm is secondary/metastatic, the appropriate liver neoplasm code is 197.7 (Secondary malignant neoplasm of respiratory and digestive systems; liver, specified as secondary), says Helget. Example: "The next diagnosis listed would be for the site being treated: liver metastasis, 197.7," Helget says, citing chapter 2.b of the guidelines. "And you should also list your primary cancer regardless of it being treated or not," she adds. For a primary colon neoplasm, choose the most appropriate code from 153.x (Malignant neoplasm of colon) or 154.x (Malignant neoplasm of rectum, rectosigmoid junction, and anus). For this example of a patient presenting solely for chemotherapy aimed at a secondary liver neoplasm, sequence your ICD-9 codes as follows, Helget says: V58.11 197.7 the appropriate 153.x-154.x code.