Prepare for more specific codes for male breast cancer patients. ICD-9-CM codes for breast neoplasms are fairly specific, but your ICD-10-CM options kick the detail requirements up another notch. Here's the lowdown on how ICD-10-CM incorporates additional anatomic information and increases the data needed when you code for male patients. ICD-9-CM coding rules: For female patients you use 174.x (Malignant neoplasm of female breast), and your fourth digit options relate to anatomic location: For male patients, you use 175.x (Male neoplasm of male breast). The fourth digit again relates to anatomic site, but the list is much shorter: ICD-9-CM instructions for both 174.x and 175.x tell you to report an additional code to identify the patient's estrogen receptor status (V86.0, Estrogen receptor positive status [ER+]; V86.1, Estrogen receptor negative status [ER-]). ICD-10-CM changes: 1. C50.- is the range for "Malignant neoplasm of breast." As with ICD-9-CM, you will use an additional code to identify estrogen receptor status (Z17.0, Estrogen receptor positive status [ER+]; Z17.1, Estrogen receptor negative status [ER-]). 2. The fourth character of the C50.- range identifies the anatomic area: nipple and areola, central portion, upper-inner quadrant, etc. One difference between ICD-9-CM and ICD-10-CM is that ICD-9-CM has an "other sites" code for the female breast. ICD-10-CM does not offer an "other sites" code. It does offer a code range for "overlapping sites": C50.8-. The range applies to male and female patients, as explained in point 3. 3. The fifth character of the C50.- range allows you to identify whether the patient is male or female. As a result, you'll need to know the precise anatomic location of the neoplasm for both male and female patients. This differs from ICD-9-CM, which has only two code options for male breast cancer patients. 4. The sixth character of the C50.- range identifies the affected breast (right, left, or unspecified). Below is an example of the ICD-10-CM code options for an upper-outer quadrant neoplasm: Coder tips: Remember: