Modifiers and test results are among the 'instant denial' triggers for these codes. Whether you search under medical oncology, hematology, or hematology/oncology, J0881 and J0885 rank first and third on the lists of the top 10 codes reported to th CMS database (2009). These J-codes for erythropoiesis stimulating agents (ESAs) carry a heavy load of very specific reporting requirements and volatile reimbursement rates. To be sure your claims for these frequently reported codes are as clean and accurate as possible, apply the tips below. Learn more: Warm Up With Code and ESA Definitions The HCPCS codes in focus are as follows: Code J0885 applies instead to supply of Epogen or Procrit. Keep in mind that the J codes represent only the supply. You should report the ESA administration separately using 96372 (Therapeutic, prophylactic, or diagnostic injection [specify substance or drug]; subcutaneous or intramuscular) for intramuscular (IM) administration, says Janae Ballard, CPC, CPC-H, CPMA, CEMC, PCS, FCS, coding manager for The Coding Source, based in Los Angeles. Both codes indicate they are specific to "non-ESRD use." ESRD is short for end stage renal disease. Consequently, these codes are appropriate when the injection is connected to oncologic use. What ESAs do: Dig In to Test Result Requirements for Coverage Read through the ESA NCD, and you'll find a list of specific conditions that indicate ESA treatment is reasonable and necessary for anemia caused by myelosuppressive anticancer chemotherapy in: Term tip: The NCD also describes recommended dosages for beginning treatment, as well as conditions for coverage to continue treatment based upon how the patient's numbers change over time (as this change indicates the efficacy of the treatment course). Additionally, the NCD states, "ESA treatment duration for each course of chemotherapy includes the 8 weeks following the final dose of myelosuppressive chemotherapy in a chemotherapy regimen." Straight from the source: Apply HGB/HCT Requirement to Your Claims Because of the above conditions, when you report J0881and J0885, Medicare requires you to report "the most recent hematocrit [HCT] or hemoglobin [HGB] reading available when the billed ESA dose was administered," according to MLN Matters MM5699. You should report the test results in item 19 if you use the CMS-1500 paper claim form, MM5699 indicates. If you use electronic claims (837P), follow this direction from MM5699: "Report the hemoglobin or hematocrit readings in Loop 2400 MEA segment. The specifics are MEA01=TR (for test results), MEA02=R1 (for hemoglobin) or R2 (for hematocrit), and MEA03=the test results. The test results should be entered as follows: TR= test results, R1=hemoglobin or R2=hematocrit (a 2-byte alpha-numeric element), and the most recent numeric test result (a 3-byte numeric element [xx.x]). Results exceeding 3-byte numeric elements (10.50) are reported as 10.5." Example: Smart moves: For instance, "having the ancillary staff write the HGB/ HCT on the charge ticket seems to be the best method for communicating the lab results," Ballard says. For clarity, "be sure that staff is consistently using either the HGB or HCT and not switching between" them, she advises. "The format for entering HGB/HCT can be different if [you're] keying outpatient hospital claims, and the charge entry staff need to know which format to use." Additionally, you can place a separate form in the chart's "Laboratory" section where the staff tracks the levels, including test dates and results. If your practice uses an electronic medical record (EMR), it may have a "lab" section showing all lab results and dates, Ballard says. "The charge entry staff could use this to find the most recent lab values," as well, she notes. Benefit: Resource: Tackle the ABCs of EA, EB, and EC Another key to proper J0881 and J0885 payment is understanding the following modifiers: Requirement: Modifier EA: Modifier EB: Modifier EC: Modifiers EA and EC are the two you're most likely to use, notes Ballard. You can find Transmittal 1413 online at www.cms.hhs.gov/transmittals/downloads/R1413CP.pdf. If you want to know which ICD-9 codes support medical necessity, you'll need to check your payer's local coverage determination (LCD). You'll often find instructions to report multiple diagnosis codes, such as a code for the anemia as well as a code for the cause of the anemia.