Question: New York Subscriber Answer: When she uses continuous RF to destroy the greater occipital nerve, report 64640 (Destruction by neurolytic agent; other peripheral nerve or branch). If she uses pulsed RF, however, CPT directs you to 64999 (Unlisted procedure, nervous system). Explanation: Continuous (a.k.a. standard or thermal) RF therapy uses continuous radio wave energy to heat up nerve tissue to a point that it creates a destruction of the target nerve. This neurolytic lesioning decreases the patient's pain by interrupting the sensory nerve pathways. In contrast, pulsed RF therapy uses shorter intermittent bursts of radio wave energy at much lower temperatures. Pulsed RF is not considered to be destructive; the technique "stuns" the target nerve tissue to prevents it from transmitting pain signals rather than directly damaging the target nerve tissue.