Question: Which agency is most appropriate to contact if I have questions about an appeal related to a National Correct Coding Initiative (NCCI) claim denial? Missouri Subscriber Answer: It may seem confusing, but if you have a question about a specific claim, even if related to NCCI, you should direct it to your assigned Medicare Administrative Contractor (MAC), not an NCCI contractor. “The NCCI Contractor is able to address general questions and concerns about the NCCI program and edits. Claim-specific inquiries must be directed to the MAC because NCCI edits are implemented by the MACs as part of routine claim processing. This includes appeals of NCCI-related denials,” the Centers for Medicare & Medicaid Services (CMS) says on its website. Refresh: CMS developed and implemented NCCI to promote standardized — correct — coding of Medicare Part B claims. Its policies are based on coding conventions defined in the AMA CPT® code book, as well as “national and local policies and edits, coding guidelines developed by national societies, analysis of standard medical and surgical practices, and a review of current coding practices,” according to the CMS website.