Question: Are there any changes relevant to pain management or neurology that we should be on the lookout for when CPT® releases its 2021 manual? Florida Subscriber Answer: Aside from the sea change in office/outpatient evaluation and management (E/M) service coding, there isn’t much to get excited about in CPT® 2021. Considering how challenging the new E/M rules will be to get a handle on, maybe a lack of important changes isn’t such a bad thing for 2021. There are, however, a few deletions that you might want to note. These codes will be invalid as of January, 1, 2021: Note: No official guidance yet on what codes you might use instead of the above codes; check with your payer to see how they would like you to code these injections in 2021.