Give the physician a heads up about these meds. A patient taking methadone and any one of the following drugs could be at risk for a drug-drug interaction, according to Jeffrey Behrens, MD, who presented on pain management at the March 2006 American Medical Directors Association meeting in Dallas. Antifungals Doxycycline Paroxetine (Paxil) Rifampin
Ciprofloxacin (Cipro) Erythromycin Phenobarbital Sertraline (Zoloft)
Clarithromycin (Biaxin) Fluoxetine (Prozac) Propofol St. John's wort (OTC herbal remedy)
Desipramine (Norpramin) Isoniazid Protease inhibitors Verapamil
Diclofenac (Voltaren) Nafcillin Quinidine