Upcoding every skin lesion to soft tissue tumor could bring fraud charges. Don't make an upcoding error that could land your practice in hot water. Follow these tips to ensure that you distinguish new CPT 2010 musculoskeletal soft tissue tumor codes from procedures better described by integumentary entries. Take a Hint From Cancer Source Soft tissue tumor excision codes and skin cancer treatment codes aren't interchangeable based on size or even depth of excision. With rare exceptions, you should use integumentary codes for skin cancers, and save the new 20000 series soft tissue tumor codes for lesions that do not arise in the dermis. Origin is key: Follow text note: Let Cancer Type Guide You If your surgeon removes a malignant melanoma that extends into the muscle, should you use the new soft tissue tumor resection codes? Almost never, says Heiner. Even if the tumor is deep, the vast majority of the time you should select from the integumentary codes for a melanoma excision. The new codes in the 20000 series are for soft tissue tumors, such as sarcomas and lipomas.